Drug Development

IN-HOUSE RD PROJECTS

Bio-Betters Drugs are new drugs designed from existing ones with improved properties such as higher efficacy, selectivity, stability, half-life, and/or lower toxicity/immunogenicity.

Projects

Super Agonist Antibody Platform

AgTa-101
(Bio-Better)

AgTa-106
(Bio-Better)

AgTa-234
(Bio-Better)

AgTa-203
(Bio-Better)

Diseases

(Platform)

Immune Diseases

Cardiovascular Diseases

Tumors

Liver Tumor

Current Status

Validating with AI and in vitro testing.

Optimizing the candidates with AI and validating in wet-lab.

Optimizing the candidates with AI and validating in wet-lab.

Optimizing the candidates with AI and validating in wet-lab.

Optimizing the candidates with AI and validating in wet-lab.

Projects

Super Agonist
Antibody Platform

AgTa-279 (Bio-Better)1

AgTa-301 (Bio-Better)

AgTa-101 (Bio-Better)

AgTa-234 (Bio-Better)

AgTa-203 (Bio-Better)

Diseases

(Platform)

Rheumatoid Arthritis

Fibrosis

IBD (UC & Crohn’s)

Tumors

Liver Tumor

Current Status

Validating with AI and In-Vitro testing.

Selecting the best candidates with AI and testing in vitro/vivo disease models

Selecting the best candidates with AI and testing in vitro/vivo disease models

Selecting the best candidates with AI and testing in vitro/vivo disease models

Screening candidates with AI and testing in vitro/vivo disease models.

Screening candidates with AI and testing in vitro/vivo disease models.

Estimated Completion Date

Q1 2025

Q4 2025

Q4 2025

Q1 2026

Q2 2026

Q2 2026

Source: Company Management estimates. Conventional antibody agonist turns on signaling thru the help of other cells’ FcR. AgTa-279 antibody can bind to a unique cryptic binding site (cryptic epitope) and turns on agonist function by itself without the help of other cells’ FcR.